Package Contents
Free Medical Consultation
Clinical Interpretation Service
What is Polygenic Risk Score (PRS)?
Your health is influenced by more than just lifestyle choices. Your genes play a crucial role in determining your risk for various diseases. The Polygenic Risk Score (PRS) Test helps you understand how your genetic makeup influences your long-term health by analyzing multiple genetic markers. Unlike traditional tests that focus on just one gene, PRS looks at a combination of genetic factors to give you a more complete picture of your health risks. It’s a proactive and personalized way to learn about your predisposition to common conditions, such as heart disease, diabetes, and even certain types of cancer.
The Polygenic Risk Score (PRS) is a measure that determines an individual's genetic predispositions. It allows us to assess disease risks by combining many genetic variants. Thus, personalized preventive health strategies can be developed.
With these insights, you can take early steps to protect your health, make smarter lifestyle choices, and even work with your doctor to create a plan that’s tailored just for you. Knowledge is power, understanding your genes gives you the opportunity to take control of your future well-being.
What Does the PRS Test Analyze?
Disease Susceptibility
- Evaluates your genetic risk for chronic diseases, including:
- Cardiovascular diseases (heart attack, stroke, hypertension)
- Diabetes & metabolic disorders
- Neurodegenerative diseases (Alzheimer’s, Parkinson’s)
- Cancer risk factors (breast, prostate, colorectal)
Genetic Influences on Health
- Assesses how multiple genetic variants interact to contribute to disease risk
- Helps identify early warning signs before symptoms appear
- Provides insights into how your body responds to external factors like diet, stress, and environment
Personalized Prevention Strategies
- Based on your PRS results, you’ll receive actionable recommendations on:
- Dietary changes and lifestyle adjustments
- Personalized exercise plans to lower disease risk
- Medical screening & early detection plans
- Medication responses for better treatment options
Polygenic Risk Score (PRS) FAQ
The PRS test analyzes multiple genetic markers together, rather than a single gene, to estimate your inherited predisposition to common conditions such as cardiovascular disease, diabetes, neurodegenerative disorders, and certain cancers. It is suitable for adults who want a proactive, personalized view of their long-term health risks, especially those with a family history of chronic disease or anyone interested in tailoring prevention, diet, and screening plans around their genetic profile.
No anesthesia or surgery is involved. The process is a simple, painless sample collection, typically a saliva sample or a small blood draw, performed at our clinic in a few minutes. The sample is then processed in a specialized laboratory, where multiple genetic variants are analyzed and combined into your individual polygenic risk score for each condition assessed.
There is no downtime or recovery period since the test itself is non-invasive. Laboratory analysis of your genetic sample generally takes a few weeks, depending on the panel selected. Once results are ready, you will review them together with our medical team, who will translate the findings into a clear, personalized action plan covering lifestyle, screening, and preventive care recommendations.
Your underlying genetic data does not change, so a single PRS test provides a lifelong reference point for your inherited disease risk. However, as genetic research advances and larger population datasets become available, risk models are periodically refined. Many patients choose to revisit their results every few years or when updated panels become available, ensuring their prevention strategy stays aligned with the latest scientific understanding.
The PRS test carries no physical risk beyond the minor discomfort of a saliva or blood sample; it leaves no scarring and requires no medication. Estetik International works with accredited genetic laboratories and experienced medical staff to ensure accurate analysis and confidential handling of your data. Combining advanced genetic testing with Turkey's high-quality, cost-effective healthcare makes it an accessible option for patients seeking proactive, personalized health insights.
Not sure yet? Talk to our doctors first.
Editor: Esra Şahinler
esra.sahinler@estetikinternational.com.tr
Last updated:
Important information!
The PRS test requires minimal preparation, but a few simple steps help ensure an accurate, smooth sample collection and a more useful consultation with your medical team.
- Gather your personal and family medical history, including any known chronic conditions among close relatives.
- Avoid eating, drinking, smoking, or chewing gum for at least 30 minutes before a saliva sample collection.
- Stay well hydrated in the days leading up to the test, particularly if a blood sample is required.
- List any current medications or supplements you take, as these may be relevant when interpreting results.
- Prepare a list of questions or specific health concerns you would like addressed during your results consultation.
- Confirm your appointment and bring valid identification for sample registration and record accuracy.
On the day of testing, the process is quick, comfortable, and requires no special recovery time.
- Check-in and a brief consultation to review your medical history and testing goals.
- Collection of a saliva sample or a small blood draw by trained clinical staff.
- Secure labeling and preparation of your sample for shipment to the genetic testing laboratory.
- Confidential laboratory analysis of multiple genetic markers to calculate your polygenic risk scores.
- Scheduling of your follow-up consultation to review results once the laboratory report is complete.
Since the PRS test is non-invasive, there is no physical recovery involved; the focus afterward is on understanding and acting on your results.
- Resume all normal activities immediately, as there are no restrictions following sample collection.
- Attend your scheduled consultation to review your results in detail with a medical professional.
- Discuss any elevated risk findings with your doctor to plan appropriate screening or preventive measures.
- Consider tailored dietary and lifestyle adjustments recommended based on your genetic profile.
- Share relevant results with your family physician to coordinate ongoing monitoring where appropriate.
- Keep a copy of your report for future reference, as it remains relevant for long-term health planning.
Top 10 requests
I had an amazing experience in Istanbul having a body lift, liposuction and BBL with Dr. B at Estetik International. The staff is absolutely amazing from transportation, to translation, and promptly answering questions. The nursing staff took amazing care of me and my husband who was able to sleep..
Stacy S.
Body Surgeries Patient